منابع مشابه
Role of Cardiolipin in Mitochondrial Signaling Pathways
The phospholipid cardiolipin (CL) is an essential constituent of mitochondrial membranes and plays a role in many mitochondrial processes, including respiration and energy conversion. Pathological changes in CL amount or species composition can have deleterious consequences for mitochondrial function and trigger the production of reactive oxygen species. Signaling networks monitor mitochondrial...
متن کاملCardiolipin-mediated mitochondrial dynamics and stress response in Arabidopsis.
Mitochondria are essential and dynamic organelles in eukaryotes. Cardiolipin (CL) is a key phospholipid in mitochondrial membranes, playing important roles in maintaining the functional integrity and dynamics of mitochondria in animals and yeasts. However, CL's role in plants is just beginning to be elucidated. In this study, we used Arabidopsis thaliana to examine the subcellular distribution ...
متن کاملCardiolipin synthesis for the assembly of bacterial and mitochondrial membranes.
In this article, the formation of prokaryotic and eukaryotic cardiolipin is reviewed in light of its biological function. I begin with a detailed account of the structure of cardiolipin, its stereochemistry, and the resulting physical properties, and I present structural analogs of cardiolipin that occur in some organisms. Then I continue to discuss i) the de novo formation of cardiolipin, ii) ...
متن کاملCardiolipin-Mediated Mitochondrial Dynamics and Stress Response in ArabidopsisC
Ronghui Pan,a,b A. Daniel Jones,b,c and Jianping Hua,d,1 aMichigan State University–Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824 bDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan 48824 cDepartment of Chemistry, Michigan State University, East Lansing, Michigan 48824 d Plant Biology Depa...
متن کاملImpact of Antioxidants on Cardiolipin Oxidation in Liposomes: Why Mitochondrial Cardiolipin Serves as an Apoptotic Signal?
Molecules of mitochondrial cardiolipin (CL) get selectively oxidized upon oxidative stress, which triggers the intrinsic apoptotic pathway. In a chemical model most closely resembling the mitochondrial membrane-liposomes of pure bovine heart CL-we compared ubiquinol-10, ubiquinol-6, and alpha-tocopherol, the most widespread naturally occurring antioxidants, with man-made, quinol-based amphiphil...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 2009
ISSN: 0005-2736
DOI: 10.1016/j.bbamem.2009.06.007